To request the test you will need the Galleri Key provided to you by AFFI
Early detection makes a difference.
The Galleri® multi-cancer early detection test screens for a signal shared by more than 50 types of cancer.1
The Galleri test should be used in addition to healthcare provider recommended screening tests. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer.
The Galleri test should be used in addition to healthcare provider recommended screening tests. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer.
Why is early detection important?
The Galleri test allows you to screen for more cancers when used in addition to single cancer screening tests.2,3 The Galleri test identifies DNA in the bloodstream shed by cancer cells and does not predict your future genetic risk for cancer.
Only 5 cancers have have recommended screening tests:
breast, cervical, colorectal, lung (for those at risk), cervical and prostate.2
The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood.
False positive and false negative results do occur.
Who is eligible?
AFFI active members and spouses of active members may request the Galleri test at a reduced cost of $649 using the Galleri Key provided to you.
The Galleri test is available by prescription only. The Galleri test is recommended for use in adults with an elevated risk for cancer, such as those aged 50 or older. The Galleri test does not detect all cancers and should be used in addition to routine cancer screening tests recommended by a healthcare provider.
Use of Galleri is not recommended in individuals who are pregnant, 21 years old or younger, or undergoing active cancer treatment.
Ordering the test
In order to request the Galleri test you will need a Galleri Key.
We suggest the use of a personal email address to request the test.
Galleri is by Prescription Only. Your test request will be reviewed by an independent telemedicine provider.
What is the Galleri test?
Galleri is a multi-cancer early detection (MCED) test that looks for a signal shared by more than 50 types of cancer.1 If a cancer signal is detected, Galleri can predict the tissue type or organ associated with the signal to help healthcare providers determine next steps.
The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer.
Our testing process
Request the test
The Galleri test is available by prescription only. You can request the test through our website from an independent telemedicine provider.
Receive a collection kit
If the independent telemedicine physician confirms you are eligible and orders your test, you can schedule a blood draw at one of GRAIL’s blood draw partners and we will ship you a Galleri collection kit for your appointment.
Provide your sample
The trained technician that draws your blood sample will ship the kit back to the GRAIL lab.
Receive your results
An independent telemedicine provider will reach out when your results are ready — about 2 weeks after your blood draw. Your test result will be shared with you by an independent telemedicine provider.
Understanding your results
You will receive your test result about two weeks after your blood sample is received at the GRAIL lab.
There are two possible results:
- No Cancer Signal Detected
- Cancer Signal Detected
Galleri looks for a signal shared by more than 50 cancer types.1 You will not receive a list of the 50+ types of cancer and a result for each one.
If Galleri detects a cancer signal, your result will include Cancer Signal Origin predictions which provides information about the tissue type or organ associated with the Cancer Signal to help healthcare providers determine next steps.
The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur.
A Galleri result of No Cancer Signal Detected does not rule out cancer.
Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer.
Frequently Asked Questions
If you are a first responder, you may request the Galleri test at a reduced cost of $649 using the Galleri Key provided to you.
“First Responder” includes firefighters, police officers, and emergency medical service providers (whether active, volunteer, or retired) and spouses/dependents.
The Galleri test is available by prescription only. The Galleri test is recommended for use in adults with an elevated risk for cancer, such as those aged 50 or older. The Galleri test does not detect all cancers and should be used in addition to routine cancer screening tests recommended by a healthcare provider. Use of Galleri is not recommended in individuals who are pregnant, 21 years old or younger, or undergoing active cancer treatment.
The test is prescription only. To access the Galleri test, you must request the test through this webpage.
When requesting through this website, an independent telemedicine provider will review your request and order the test, if appropriate.
When requesting the Galleri test you will need to provide an “Galleri Key” to confirm eligibility for the benefit. You can find your Galleri Key on the communication you received.
GRAIL is a healthcare company pioneering new technologies to advance early cancer detection. GRAIL is the first company that manufactures the Galleri multi-cancer early detection test. You may receive information or communications from GRAIL or Galleri about your benefit or the Galleri test.
The Galleri test, a multi-cancer early detection (MCED) test, is a qualitative, next-generation sequencing (NGS)-based screening test to detect a DNA methylation (cancer) signal and predict the cancer signal origin from cell-free DNA isolated from peripheral whole blood.
The Galleri test identifies DNA in the bloodstream shed by cancer cells and does not predict future genetic risk for cancer.
All cells in your body, including cancer cells, release DNA fragments into the bloodstream. These fragments are called cell-free DNA. The Galleri test screens your blood sample for cell-free DNA and identifies whether it comes from healthy or cancer cells. Cell-free DNA from cancer cells also contains information about the organ or tissue of origin. The process uses advanced technology and pattern recognition to detect a Cancer Signal and if a cancer signal is detected, predict the Cancer Signal Origin. This information helps guide healthcare providers to perform a diagnostic evaluation for cancer.
Cancer risk increases for everyone as they age, regardless of family history—only 5% to 10% of cancers are inherited.
Age is the biggest risk factor for cancer. In fact, adults over age 50 are 13 times more likely to have cancer compared to people under the age of 50.
Galleri detects a signal shared by multiple cancers. In a clinical study, Galleri detected a signal shared by over 50 types of cancer —including some fast-spreading and aggressive cancers responsible for approximately two-thirds of cancer deaths. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur.
Most people who take the Galleri test will receive a “No Cancer Signal Detected” result. A “Cancer Signal Detected” result is expected in approximately 1% of Galleri tests in people over 50 years of age.
The Galleri test accuracy is measured through Positive Predictive Value and False Positive Rates.
- Positive Predictive Value (PPV) is the proportion of people with "CancerSignal Detected" results diagnosed with cancer.
- False Positive is the proportion of people without cancer who received "Cancer Signal Detected" results.
In a recent study, the PPV was 43.1% for study participants with a Cancer Signal Detected result who were diagnosed with cancer. The False Positive Rate was 0.5% for participants without cancer. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer.
No, Galleri is not a genetic risk assessment test. A genetic risk assessment is a one time measurement and assesses the future risk of developing cancer. Genetic tests may look at DNA and assess lifelong risk for cancer but cannot detect if a person currently has cancer.
The Galleri test looks for a signal associated with active cancer at the time of your blood draw. Regularly using the Galleri test, alongside recommended cancer screenings, can increase your chance of detecting cancer early.
No, the Galleri test is only commercially available in the US.
Schedule a time and place convenient for you. Visit: Galleri.com/schedule to select either
- A partner lab
- A mobile phlebotomy option.
- A trained technician will come to your home, office, or any preferred location to complete your blood draw
Learn more about how your sample is processed at the GRAIL laboratory by watching this video.
Once you receive your sample collection kit, please do not break the quality seal on it. The collection kit should be opened by the trained technician who draws your blood sample.
Store the kit at room temperature until your blood draw appointment. The contents are sensitive to extreme temperatures. For example, do not store the collection kit in a car.
To schedule your blood draw visit: Galleri.com/schedule
The trained technician who draws your blood will pack and ship your sample back to the GRAIL laboratory for processing. Everything needed to complete the blood and return the sample is within the Galleri sample collection kit.
If you or your blood draw technician has questions, please call Customer Service: (833) 694‑2553
No, fasting is not required for the Galleri test.
Approximately 1.5 tablespoons (or about 20 mL) of blood in two tubes from a vein in your arm.
If you no longer wish to receive your Galleri results, contact GRAIL Customer Service by calling (833) 694‑2553.
Your sample will arrive at the GRAIL lab one to two days after your blood draw. Test results will be available about two weeks after your sample is received at the GRAIL lab.
If you participated in an onsite blood draw sponsored by your employer results may take as long as three weeks.
Your test results will be shared with you by the ordering provider. GRAIL will email your results to you.
Your test results can be requested by contacting GRAIL Customer Service by calling (833) 694‑2553.
The Galleri test detected DNA methylation patterns that are often associated with cancer in your blood sample. About 1 out of every 100 tests has a Cancer Signal Detected result.3
This result will also include a prediction of the tissue type or organ associated with the cancer signal, called a Cancer Signal Origin. This helps your doctor determine the next steps for diagnosis.
Results should be interpreted by a healthcare provider. This test result is not a cancer diagnosis and requires follow-up diagnostic testing which may include lab work or imaging ordered by your healthcare provider to confirm cancer. GRAIL also offers patients and providers additional support and resources if needed to help guide next steps.
False positive and false negative results do occur.
The Galleri test did not detect DNA methylation patterns that are associated with cancer in your blood sample. Nearly 99% of people who use the Galleri test, will receive a No Cancer Signal Detected result.3
This result does not completely rule out the possibility of cancer. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. This result does not predict whether you will develop cancer in the future.
The Galleri test can be taken as an annual blood test. Adding the Galleri test to annual wellness visits allows you to go further with cancer screenings. Ask your healthcare provider when is best to test again.
False negative results do occur.
The Galleri test is intended to be used in addition to, and not replace, other cancer screening tests your healthcare provider recommends. Single-cancer screening tests are recommended because they have been proven to save lives by detecting cancer early. Using Galleri in addition to recommended single-cancer screenings can increase your chances of detecting cancer early, when there may be more treatment options.
Galleri does not detect a signal for all cancers and not all cancers can be detected in the blood.
A Cancer Signal Detected test result is not a cancer diagnosis. A Cancer Signal Detected result requires follow-up diagnostic testing which may include lab work or imaging ordered by your healthcare provider. GRAIL also offers patients and providers additional support and resources if needed to help guide next steps.
All results are automatically shared with the provider who ordered the test. When requesting the test, you may provide the information for your primary care provider.
If you would like us to fax your results to an additional healthcare provider, please contact Customer Service by calling (833) 694‑2553 to receive instructions on how to complete a results release form.
Get support
For questions about the Galleri test, please contact GRAIL Customer Service:
By email: customerservice@grail.com
By telephone: (833) 694‑2553
The Galleri test is recommended for use in adults with an elevated risk for cancer, such as those age 50 or older. The test does not detect all cancers and should be used in addition to routine cancer screening tests recommended by a healthcare provider. The Galleri test is intended to detect cancer signals and predict where in the body the cancer signal is located. Use of the test is not recommended in individuals who are pregnant, 21 years old or younger, or undergoing active cancer treatment.
Results should be interpreted by a healthcare provider in the context of medical history, clinical signs, and symptoms. A test result of No Cancer Signal Detected does not rule out cancer. A test result of Cancer Signal Detected requires confirmatory diagnostic evaluation by medically established procedures (e.g., imaging) to confirm cancer.
If cancer is not confirmed with further testing, it could mean that cancer is not present or testing was insufficient to detect cancer, including due to the cancer being located in a different part of the body. False positive (a cancer signal detected when cancer is not present) and false negative (a cancer signal not detected when cancer is present) test results do occur. Rx only.
The GRAIL clinical laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and accredited by the College of American Pathologists. The Galleri test was developed — and its performance characteristics were determined — by GRAIL. The Galleri test has not been cleared or approved by the Food and Drug Administration. The GRAIL clinical laboratory is regulated under CLIA to perform high-complexity testing. The Galleri test is intended for clinical purposes.
Klein EA, Richards D, Cohn A, et al. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set. Ann Oncol. 2021;32(9):1167-77. DOI: https://doi.org/10.1016/j.annonc.2021.05.806.
US Preventive Services Task Force (USPSTF) recommended cancer screening tests, Grade A,B,C. https://www.uspreventiveservicestaskforce.org/uspstf/topic_search_results
Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): a prospective cohort study. Lancet. 2023;402:1251-1260. doi: 10.1016/S0140-6736(23)01700-2.