The Galleri® test
detects more than 50 types of cancer through a simple blood drawWhat if you found cancer early enough to make a difference?
The Galleri multi-cancer early detection test from GRAIL can screen for more than 50 types of cancer by looking for a shared cancer signal and pointing to where in the body a signal may be coming from. The Galleri test is the latest groundbreaking innovation added to the John Hancock Vitality Program.
Patient Testimonial
Not registered for John Hancock Vitality yet?
You need to activate your Vitality account before you can request your Galleri test.
Key benefits of the Galleri test
Early cancer detection
Designed to detect many cancers that are not commonly screened for, to allow for earlier diagnosis and treatment.1
Testing with ease
Completed with a simple blood draw.
Actionable results
If a cancer signal is found, the results can point to where in the body the cancer signal may be coming from to help your personal physician guide your next steps.
The Galleri test does not detect all cancers and should be used in addition to routine cancer screening tests recommended by a healthcare provider.
Who is eligible?
Eligibility requirements:
John Hancock is offering the Galleri test to registered Vitality PLUS members who have completed the Vitality Health Review in the current program year. Members must be at least 50 years old and meet GRAIL’s clinically informed criteria to participate. Availability may vary by state.
There are two possible test results
No Cancer Signal Detected
No cancer signal was found. However, not all cancers can be detected by the Galleri test, and in particular, the sensitivity rate for detecting cancer in the early stages is lower than for later stages.
Continue with all routine screening tests that your healthcare provider recommends. Missing routine cancer screenings or ignoring symptoms could lead to a delayed diagnosis of cancer.
Cancer Signal Detected
There is a suspicion of cancer. The Galleri test can point to where in the body the cancer signal is coming from.
The Galleri test does not diagnose cancer. You should discuss appropriate follow-up testing with your personal healthcare provider to confirm if cancer is present. There may be additional costs for such diagnostic testing.
Important information about your results:
False positive and false negative results do occur. The Galleri test does not detect all cancers. Not all cancers can be detected in the blood.
Keep in mind that you will not receive a list of the 50+ types of cancer Galleri can screen for and a result for each one.
The Galleri test does not measure your genetic risk of developing cancer in the future. It’s important to continue with any additional screenings your healthcare provider recommends. The Galleri test is currently not approved by the U.S. Food and Drug Administration.
Still wondering what to expect from your result? Learn more about test results.
Frequently asked questions
John Hancock is offering the Galleri test to registered Vitality PLUS members who have completed the Vitality Health Review in the current program year. Members must be at least 50 years old and meet GRAIL’s clinically informed criteria to participate. Availability may vary by state.
If you received an email from John Hancock Vitality offering you access to the Galleri test, take note of your unique Access ID and complete the steps to request your test at Galleri.com/JHVAccess.
Please note: Galleri is not recommended for individuals who are pregnant or undergoing active cancer treatment.
The Galleri test is designed to detect many cancers that are not commonly screened for today which can allow for earlier diagnosis and consideration of more treatment options. A positive Galleri test result should be followed by an appointment with your primary care physician and appropriate diagnostic tests to confirm cancer status. There may be additional costs for such diagnostic testing.
For details on the cost of requesting your Galleri test, please refer to the email you received from John Hancock Vitality that also contains your unique Access ID.
If you choose to complete the blood draw at a lab not on GRAIL’s approved partner list, including your primary healthcare provider’s office, you will be responsible for the blood draw fee per your health insurance provider’s requirements.
In the event of a “Cancer Signal Detected” test result, you will be responsible for the cost of follow-up diagnostic procedures (e.g., imaging, biopsies, other laboratory tests, etc.). You may incur cost share expenses such as co-pays, deductibles, and co-insurance with your health insurance provider. Please contact your health insurance plan to determine covered expenses and your potential costs related to follow-up procedures that your healthcare provider may recommend.
There is no coordination of benefits between John Hancock and any health benefits you may receive from an insurance policy, health plan, or any other wellness programs you may be enrolled in.
The tax treatment of the Galleri test offered in connection with the Vitality Program is uncertain. At this time, John Hancock does not expect that it will be required to report the value of the Galleri test to the IRS as income to the insured. You should consult your own tax professional.
John Hancock Vitality members who are notified of the offer via email can request the test through GRAIL’s patient portal, via Galleri.com/JHVAccess.
Once you complete the online test request form, a healthcare provider from PWNHealth, GRAIL’s independent telemedicine provider, will review your request and clinical eligibility within one week. They will approve your request and order the test if appropriate.
To be eligible for this offer, John Hancock Vitality PLUS members must request their test on the John Hancock Galleri web page using their unique Galleri Access ID (sent via email from John Hancock Vitality). However, members may consult with their primary care physician in advance if they have questions.
Once the member requests the test, an independent healthcare provider from PWNHealth, GRAIL’s telemedicine partner, will review your request and order the test if appropriate.
When you request the test, PWNHealth gives you the option to enter your primary healthcare provider’s contact information, so that PWNHealth can automatically share your results if a cancer signal is detected. If no cancer signal is detected, you can share the results with your provider, but results will not be sent by PWNHealth to anyone other than you.
The Galleri test is only available to John Hancock Vitality PLUS members whose eligibility is evaluated and confirmed by PWNHealth, GRAIL’s partner telemedicine provider (see Question #1 above for additional information).
If you are not eligible under the terms of John Hancock’s offer (i.e., due to policy issue state) but would still like to learn more about the test, visit Galleri.com. You would be responsible for the cost of the test and provider services.
The Galleri test is currently available to John Hancock Vitality members whose eligibility is evaluated and confirmed by PWNHealth, GRAIL’s partner telemedicine provider (see Question #1 above for additional information).
Other family members are not eligible for this John Hancock offer but may learn more about the test and request it at Galleri.com. The family member would be responsible for the cost of the test and provider services.
John Hancock is committed to helping its customers live longer, healthier, better lives by offering them the latest tools and technology that can help them better understand their health and make informed choices.
The Galleri test is designed to detect many cancers that are not commonly screened for today, to allow for earlier diagnosis and treatment. John Hancock wants to make customers aware of the technology so that they can decide if taking the test is right for them.
John Hancock and Vitality will not receive individual test results and results will have no impact on your current life insurance coverage.
As part of this offer, eligible John Hancock Vitality members are limited to one Galleri test.
The Galleri test is a multi-cancer, early detection test that uses a single blood draw to screen for more than 50 types of cancer, many of which are not commonly screened for today. The Galleri test does not diagnose cancer and not all cancers may be detected in the blood.
The Galleri test is intended to be used in addition to, and not in lieu of, other cancer screening tests your healthcare provider recommends.
The Galleri test does not detect all cancers, nor does it measure your genetic risk of developing cancer in the future. A test result of “Cancer signal not Detected” does not rule out cancer, and in particular, the sensitivity rate for detecting cancer in the early stages is lower than for later stages.
The Galleri test looks for signals present in the blood that may be associated with cancer at the time of your blood draw. If a cancer signal is detected, the results can point to where in the body the cancer signal is coming from to help your healthcare provider guide next steps.
Family history is only one of many risk factors associated with cancer development. Other risk factors include eating habits, lifestyle, living or working environments, genetics, and many others.
When you submit your test request, you may ask for a pre-test consultation with a PWNHealth provider to discuss whether the test is right for you. This optional consultation is included in the offer. Additionally, we suggest speaking with your primary care physician.
Your test results will not impact your premiums or risk class on your current (inforce) policies, either positively or negatively. Results will also not impact your Vitality Status.
If an individual receives a “cancer signal detected” result from the Galleri test and follow-up diagnostic testing confirms a cancer diagnosis, it could impact insurability or premiums if they subsequently apply for additional life insurance coverage — as is the case with a cancer diagnosis that results from many other commonly used diagnostic tools that are reviewed during the underwriting process.
If an individual receives a “cancer signal detected” result but does not follow up with their physician and then applies for additional coverage, John Hancock would request appropriate clinical follow up with the insured’s physician, consistent with standard underwriting practices.
Existing cancer or cancer that is in remission would need to be disclosed in most insurance applications. This does not necessarily mean that new policy applications would be declined or require higher premiums.
In a clinical validation study (CCGA3*), the Galleri test detected more than 50 types of cancer across all stages.
The Galleri test is intended to be used in addition to and not replace other cancer screening tests and can help maximize the benefits of early cancer detection. Missing recommended screenings or ignoring symptoms could lead to a delayed diagnosis of cancer.
Based on data from GRAILS’s studies, the Galleri test has shown a low false positive rate of 0.5% in non-cancer participants (detects a cancer signal when no cancer is present). This means in the clinical studies, in approximately 200 non-cancer participants, 1 participant received a positive (false positive) test.
The Galleri test development was supported by what is believed to be one of the largest clinical study programs in genomic medicine, with over 20,000 participants at more than 140 clinical study sites, including the Mayo Clinic, Dana-Farber Cancer Institute, Cleveland Clinic, Sutter Health, OHSU, Intermountain Healthcare, and U.S. Oncology Network.
The Galleri test has not been cleared or approved by the FDA. GRAIL’s clinical laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and accredited by the College of American Pathologists (CAP). GRAIL’s clinical laboratory is regulated under CLIA to perform high-complexity testing.
You need your unique Galleri Access ID. If you are eligible for the offer, you should have received your Galleri Access ID from John Hancock Vitality via email. If you cannot locate your ID, please contact John Hancock Vitality at 888−333−2659. You cannot request your test at Galleri.com/JHVAccess without your Galleri Access ID.
A healthcare provider from PWNHealth will review your request and clinical eligibility within one week. They will approve your request and order the test if appropriate.
If the PWNHealth provider approves your request, you will be shipped a Galleri collection kit and receive an email confirmation with instructions for how to schedule your blood draw.
When your collection kit arrives, you can schedule a blood draw appointment at one of GRAIL’s partner labs or mobile phlebotomy provider. Test results will be ready about two weeks after your sample is received at GRAIL.
If your Galleri test request is approved and your collection kit has arrived, you can schedule a blood draw appointment with one of GRAIL’s partner labs or mobile phlebotomy provider.
Please note that completing your blood draw at some place other than one of GRAIL’s partner labs will not be covered by this offer.
Bring your unopened Galleri sample collection kit and your completed and printed ‘Test Requisition Form’ to your blood draw appointment.
You will receive these items if your eligibility for the Galleri test is approved. A collection kit will be mailed to you within one week after your request is approved. Do not break the quality seal on the collection kit. It should be opened by the lab technician who draws your blood sample. A completed Test Requisition Form will be emailed to you from GRAIL. Remember to print the form and bring it to your appointment.
The Test Requisition Form is the ordering form PWNHealth completes to order the test for you.
You will receive this document via an order confirmation email from GRAIL if the provider orders your test.
No preparation or fasting is required. Some lab technicians may ask if you have fasted (no eating or drinking), but this is not required for the Galleri test.
Please do not break the quality seal on the collection kit. It should be opened by the lab technician who draws your blood sample.
Store the collection kit at room temperature until your blood draw appointment. The contents are sensitive to extreme temperatures. For example, avoid storing your collection kit in the trunk of your car.
Your next step is to schedule your blood draw at a GRAIL partner lab. There is also a mobile phlebotomy option.
The collection kit includes instructions for the lab technician, two tubes for the blood sample, and packing materials to ensure the sample is safely shipped to GRAIL.
Please do not break the quality seal on the collection kit. It should be opened by the lab technician who draws your blood sample.
The lab technician who draws your blood will pack and ship your sample back to GRAIL for processing.
Your sample will arrive at GRAIL 1 to 2 business days after your blood draw.
Approximately 1.5 tablespoons (or about 20 mL) of blood in two tubes typically from a vein in your arm.
It takes about two weeks after your blood sample is received at GRAIL to receive your Galleri test results from the PWNHealth provider that ordered your test.
Your sample will arrive at the GRAIL lab one to two business days after your blood draw. Your results should be available to the PWNHealth provider who ordered your test within 10 business days (Mon — Fri excluding holidays) from the time your sample is received at GRAIL.
If you no longer wish to receive your Galleri results, please contact PWNHealth to request a cancellation at gc@pwnhealth.com or 888−494−7333.
If you require further assistance, please contact GRAIL Customer Service at customerservice@grail.com.
This means that no cancer signal was found. However, not all cancers can be detected by the Galleri test and in particular, the sensitivity rate for detecting cancer in the early stages is lower than for later stages. Continue with all routine screening tests that your healthcare provider recommends. Missing routine screenings or ignoring symptoms can lead to a delayed diagnosis of cancer.
PWNHealth also offers optional post-test counseling to discuss your result, which is included in your offer.
This means additional tests are needed to confirm if you have cancer. The PWNHealth provider who ordered your test will share this result with you and what it may mean.
When you request the test, you are given the option to enter your primary healthcare provider’s contact information, so that PWNHealth can automatically share your result if a cancer signal is detected. If you do not have a primary healthcare provider, PWNHealth can help you find one in your area.
The Galleri test can point to where in the body the cancer is coming from with high accuracy to help your primary healthcare provider guide next steps. Your primary healthcare provider should order appropriate follow-up testing to confirm if cancer is present.
In the event that a diagnostic evaluation after a “cancer signal detected” result with Galleri does not confirm cancer, you may be eligible for a complimentary Galleri re-test directly from GRAIL.
The request for a re-test must be placed by the healthcare provider managing your diagnostic evaluation. The re-test must be administered within 3 – 6 months after the initial Galleri test.
To initiate a request for a re-test, your healthcare provider should contact GRAIL Customer Service at 833-MY-GALLERI (833−694−2553) or customerservice@grail.com. John Hancock does not pay for re-tests due to a false positive.
Galleri is a test that screens for the presence of cancer in the blood and provides information on where in the body the cancer may be located. The Galleri test is not a diagnostic test. Additional tests ordered by your primary healthcare provider are needed to confirm if cancer is present — which may include blood work, imaging, or certain invasive procedures.
In the event of a “Cancer Signal Detected” test result, this offer from John Hancock Vitality does not cover or pay for follow-up diagnostic procedures (e.g., imaging, biopsies, other laboratory tests, etc.). You may incur cost share expenses such as co-pays, deductibles, and co-insurance from your health insurance provider. Please contact your health insurance plan to determine covered expenses and your potential costs related to follow-up procedures that your healthcare provider may recommend.
There is no coordination of benefits between John Hancock and any health benefits you may receive from an insurance policy, health plan, or any other wellness programs you may be enrolled in.
Yes, when you request the test, PWNHealth gives you the option to enter your primary healthcare provider’s contact information so that your test results can be shared if a cancer signal is detected.
PWNHealth will not automatically share a No Cancer Signal Detected result, but we encourage you to share it with your primary healthcare provider.
The prescribing healthcare provider from PWNHealth will receive the results and share them with you. Your results and medical information are confidential, and access is limited to individuals who need the information for a specific purpose.
For example, if a cancer signal is detected, your Galleri test result will be shared with your primary healthcare provider only if you gave their contact information so that they can guide your next steps.
John Hancock and John Hancock Vitality will not receive any individual test results.
Still have questions? Here’s who to contact:
For eligibility and Access ID questions or privacy concerns, please contact Vitality Customer Care at 888−333−2659
(8am — 6pm EST) or email support@jhvitality.com
For all other questions (e.g., ordering the test, receiving the test, getting the blood draw, or test results), please contact GRAIL Customer Service at 833−694−2553 (8am — 8pm EST M‑F) or email customerservice@grail.com.
Klein EA, et al. Ann Oncol. 2021;32(9): 1167 – 1177. doi: 10.1016/j.annonc.2021.05.806.
Important safety information
The Galleri test is recommended for use in adults with an elevated risk for cancer, such as those aged 50 or older. The Galleri test does not detect all cancers and should be used in addition to routine cancer screening tests recommended by a healthcare provider. Galleri is intended to detect cancer signals and predict where in the body the cancer signal is located. Use of Galleri is not recommended in individuals who are pregnant, 21 years old or younger, or undergoing active cancer treatment.
Results should be interpreted by a healthcare provider in the context of medical history, clinical signs and symptoms. A test result of“Cancer Signal Not Detected” does not rule out cancer. A test result of“Cancer Signal Detected” requires confirmatory diagnostic evaluation by medically established procedures (e.g. imaging) to confirm cancer.
If cancer is not confirmed with further testing, it could mean that cancer is not present or testing was insufficient to detect cancer, including due to the cancer being located in a different part of the body. False-positive (a cancer signal detected when cancer is not present) and false-negative (a cancer signal not detected when cancer is present) test results do occur. Rx only.
Laboratory / Test information
GRAIL’s clinical laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and accredited by the College of American Pathologists (CAP). The Galleri test was developed, and its performance characteristics were determined by GRAIL. The Galleri test has not been cleared or approved by the Food and Drug Administration. GRAIL’s clinical laboratory is regulated under CLIA to perform high-complexity testing. The Galleri test is intended for clinical purposes.
Disclaimer
John Hancock does not provide medical advice, is not involved in the design or manufacture of the Galleri test and is not responsible for the accuracy or performance of the Galleri test. A test result of “Cancer Signal Not Detected” does not rule out cancer, and in particular the sensitivity rate for detecting cancer in early stages is lower than for later stages. Galleri does not replace routine cancer screenings. Galleri is not a test to rule out genetic or other conditions that may indicate a predisposition to cancer. There is no coordination between John Hancock and any health insurance or other benefits plan you may be enrolled in. You may incur additional costs for diagnostic screenings recommended by your healthcare provider.
Like other medical tests you elect, a decision to take the Galleri test, and the results of the test, may need to be disclosed in an application for insurance coverage, and so could affect your access to future insurance coverage and the price of such coverage.
The tax treatment of the Galleri test offered in connection with the Vitality Program is uncertain. At this time, John Hancock does not expect that it will be required to report the value of the Galleri test to the IRS as income to the insured. This material does not constitute tax or legal advice and neither John Hancock nor any of its agents, employees or registered representatives are in the business of offering such advice. You should consult your own tax professional.
The Galleri test is only available to registered John Hancock Vitality PLUS members who are 50 years of age or older and have completed the Vitality Health Review (VHR) for the current program year. The offer of discounted access to the Galleri test is subject to change. Availability of the Galleri test offer from John Hancock may vary by state.
Vitality is the provider of the John Hancock Vitality Program in connection with policies issued by John Hancock. John Hancock Vitality Program rewards and discounts are available only to the person insured under the eligible life insurance policy, may vary based on the type of insurance policy purchased and the state where the policy was issued, are subject to change and are not guaranteed to remain the same for the life of the policy. Life insurance policies and/or associated riders and features may not be available in all states.
Insurance products are issued by: John Hancock Life Insurance Company (U.S.A.), Boston, MA 02116 (not licensed in New York) and John Hancock Life Insurance Company of New York, Valhalla, NY 10595.
©2022, GRAIL, LLC. ALL RIGHTS RESERVED. GALLERI IS A TRADEMARK OF GRAIL, LLC. John Hancock is not an affiliate of GRAIL. All product and company names are the trademarks of their original owners. The use of any trade name or trademark is for identification and reference purposes only and does not imply any association with the trademark holder or its product brand.
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